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Sequential development of 2 connective tissue diseases in juvenile patients.

Gustavo Citera, Graciela Espada, J A Maldonado Cocco

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Abstract

The sequential development of two connective tissue diseases in the same patient has been rarely reported. We describe 2 juvenile patients, a 15-year-old girl who, after having juvenile rheumatoid arthritis (JRA) for a 7-year period presented with clearly defined features of systemic lupus erythematosus with diffuse proliferative glomerulonephritis. The 2nd case, a 9-year-old boy developed erosive polyarticular JRA after having had a clear picture of dermatomyositis in infancy. In both cases there was a lengthy disease free period between the 2 diseases.

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What this paper is about

The sequential development of two connective tissue diseases in the same patient has been rarely reported. We describe 2 juvenile patients, a 15-year-old girl who, after having juvenile rheumatoid arthritis (JRA) for a 7-year period presented with clearly defined features of systemic lupus erythematosus with diffuse proliferative glomerulonephritis. The 2nd case, a 9-year-old boy developed erosive polyarticular JRA after having had a clear picture of dermatomyositis in infancy. In both cases there was a lengthy disease free period between the 2 diseases.

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Available abstract

The sequential development of two connective tissue diseases in the same patient has been rarely reported. We describe 2 juvenile patients, a 15-year-old girl who, after having juvenile rheumatoid arthritis (JRA) for a 7-year period presented with clearly defined features of systemic lupus erythematosus with diffuse proliferative glomerulonephritis. The 2nd case, a 9-year-old boy developed erosive polyarticular JRA after having had a clear picture of dermatomyositis in infancy. In both cases there was a lengthy disease free period between the 2 diseases.

Key concepts: Juvenile dermatomyositis, Medicine, Juvenile rheumatoid arthritis, Connective tissue disease, Connective tissue, Dermatomyositis, Juvenile, Arthritis

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