[Serological typing of HLA].

Micro-lymphocyte cytotoxicity test (LCT) have been developed by Dr. Terasaki at 1964 and usually used for serological typing up to date. HLA typing has been complicated by the extensive diversity of and the sequence homology among HLA alleles. However, it is need to match HLA types between donor and patient for hematopoietic stem/progenitor cell transplantation, therefore accurate HLA typing is required. Recently, it is able to perform accurate lymphocyte separation and HLA typing of much blood samples by using immunomagnetic beads and computer analysis, respectively.