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[ACTH-adenylate cyclase in adipose cell "ghosts" of rats with spontaneous hypertension (effect of adrenalectomy)].

Reznikova Mb, Iu V Postnov

Abstract

Basal, NaF- and ACTH-stimulated activity of adenylate cyclase was studied in "shadows" of fatty cells from intact and adrenalectomized rats with spontaneous hypertension (SHR strain) as compared with the corresponding controls. Activity of ACTH-adenylate cyclase was decreased in control adrenalectomized animals; the enzymatic activity was similar in normal rats, in adrenalectomized animals of the SHR strain and in the intact SHR rats. Basal and NaF-stimulated activities of adenylate cyclase were the same in all the animal groups studied.

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Available abstract

Key concepts: Adenylate kinase, Cyclase, Internal medicine, Endocrinology, Basal (medicine), Adipose tissue, Adrenalectomy, Chemistry