2011•Medicinal plantRequires access
Optimization of the Extraction Process of Geniposide from FRUCTUS GARDENIAE by Orthogonal Design
Jian You, Deng Qing-yun, Gao Li, Jiao Lei, Li Guoyuan
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Abstract
[Objective] To optimize the extraction process of geniposide from FRUCTUS GARDENIAE.[Method] Taking the extraction rate of geniposide as index,orthogonal test designed with 3 investigation objects including solid-liquid ratio,extraction temperature and extraction time was performed to optimize the extraction process of geniposide from FRUCTUS GARDENIAE on the basis of single factor test.[Results] The optimal extraction conditions of geniposide were as follows:60% alcohol as extracting solvent,solid-liquid ratio of 1:4,extraction temperature of 75 ℃,extraction time of 3 h.Under the above conditions,the extraction rate of geniposide reached as high as 12.59%.[Conclusion] The efficiency and stability of geniposide could be improved by suitable extraction conditions.