A Case of Verruca Vulgaris Treated with Imiquimod

Despite numerous therapeutic options the treatment of verruca vulgaris remains difficult and various treatment modalities are accompanied with substantial pain, tissue destruction and frequent recurrence. Recently imiquimod has been successfully used as topical immune response modifier for the treatment of external anogenital warts with less pain, destruction and fewer recurrent rate. We observed a case of verruca vulgaris on the left palm and the left second toe in a 57-year-old man. He had been treated with keratolytic agent and CO laser with little effect. So we tried to treat him with 5% imiquimod cream which was self-applied to the lesions and achieved complete clearance after 4 weeks of the therapy. (Korean J Dermatol 2003;41(2) : 261-263)