Clinical correlative study between the serum s-100β,NSE and acute cerebral infarction

Objective To explore the changes of the serum S-100βand NSE and evaluate the clinical significance of these two indexes in patients with acute cerebral infarction.Methods 80 cases of acute cerebral infarction were selected.The concentration of S-100βand the level of NSE in blood plasm of these patients were detected dynamically with application of ELISA.and compared with 40 healthy examinations(control group).Results The levels of S-100β and NSE in serum of patients with acute cerebral infarction were markedly higher than those in the control group (P0.05).The content s of NSE and S-100βin patients blood plasm were positively correlated with the volume of infraction and neurological deficit scores (P0.05).Conclusion The level of serum NSE and S-100β can reflect the volume of infraction and neurological deficit scores.NSE and S-100β can be used as a valuable tools for progrostic parameter of estimating lesion range,clinical stroke treatment and clinical stroke treatment.