2006•Journal of Shandong University of Traditional Chinese MedicineRequires access

Study on blood stasis and bleeding changes of anaemia rat model and clinical significance

Xin Peng

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Abstract

Objective:Discuss the mechanism and clinical meaning of blood stasis model by observing the blood routine,coagulation time of the normal group and youth,senior model with injection of APH to produce rat model of the deficiency of blood.Results:The haemorheology,blooding time,coagulation time and foot microcirculation of the model group were significant different from the normal group.The whole blood viscosity,plasm viscosity,whole blood reduced viscosity,red blood cell deformation and rigidity index increased significantly.And dysfunctional foot microcirculation and blooding time,coagulation time were prolonged(P0.01 or P0.05).There were ischemia,blood stasis,and bleeding of the organ tissue.Conclusion:Blood stasis induced bleeding have relation with the abnormality of haemorheology and coagulation function.The study can provide the evidence of treatment of enriching and regulating blood.

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What this paper is about

Objective:Discuss the mechanism and clinical meaning of blood stasis model by observing the blood routine,coagulation time of the normal group and youth,senior model with injection of APH to produce rat model of the deficiency of blood.Results:The haemorheology,blooding time,coagulation time and foot microcirculation of the model group were significant different from the normal group.The whole blood viscosity,plasm viscosity,whole blood reduced viscosity,red blood cell deformation and rigidity index increased significantly.And dysfunctional foot microcirculation and blooding time,coagulation time were prolonged(P0.01 or P0.05).There were ischemia,blood stasis,and bleeding of the organ tissue.Conclusion:Blood stasis induced bleeding have relation with the abnormality of haemorheology and coagulation function.The study can provide the evidence of treatment of enriching and regulating blood.

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Available abstract

Objective:Discuss the mechanism and clinical meaning of blood stasis model by observing the blood routine,coagulation time of the normal group and youth,senior model with injection of APH to produce rat model of the deficiency of blood.Results:The haemorheology,blooding time,coagulation time and foot microcirculation of the model group were significant different from the normal group.The whole blood viscosity,plasm viscosity,whole blood reduced viscosity,red blood cell deformation and rigidity index increased significantly.And dysfunctional foot microcirculation and blooding time,coagulation time were prolonged(P0.01 or P0.05).There were ischemia,blood stasis,and bleeding of the organ tissue.Conclusion:Blood stasis induced bleeding have relation with the abnormality of haemorheology and coagulation function.The study can provide the evidence of treatment of enriching and regulating blood.

Key concepts: Blood stasis, Microcirculation, Blood viscosity, Medicine, Coagulation, Erythrocyte aggregation, Hemorheology, Internal medicine

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