2006•Hebei yixueRequires access

Expression and Clinical Significance of PCNA,p53 Protein and hTERT in Cervical Lesion

Yulian Wang

Abstract

Objective: To investigate the clinical significance and the expression of PCNA,P53 protein and hTERT in cervical lesion tissues.Method: Immunohistochemistry was used to examine the expression of PCNA,p53 protein and hTERT in 22 cervical erosion tissues and 38 cervical intraepithelial neoplasia(CIN) tissues and 20 cervical carcinoma tissues.Result: The expression of PCNA,p53 protein and hTERT showed an increasing tendency from 22 normal cervical tissues to 38 CIN tissues,then to 20 cervical carcinoma tissues.Conclusion: The expression of PCNA,p53 protein and hTERT plays an important role in the development and malignant changes of cervical carcinoma.

About this research paper

What this paper is about

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Proliferating cell nuclear antigen, Medicine, Immunohistochemistry, Cervical carcinoma, Cervical intraepithelial neoplasia, Telomerase reverse transcriptase, Clinical significance, Lesion