2012•Zhongguo weishengtaixue zazhiRequires access
Inhibitory activity of antibacterial material of Pseudomonas aeruginosa against methicillin-resistant Staphylococcus aureus
Shi Qin-luo
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Abstract
Objective To evaluate the in vitro inhibitory activity of antibacterial material of Pseudomonas aeruginosa against methicillin-resistant Staphylococcus aureus(MRSA).Methods In vitro inhibitory activity of antibacterial material of Pseudomonas aeruginosa against 32 strains of MRSA was determined by using cross streak assay.Results In vitro inhibitory activity of antibacterial material of Pseudomonas aeruginosa against MRSA appeared satisfactory.Of the 15 strains of Pseudomonas aeruginosa,7 strains(produced blue-green pigment) showed 100% inhibition rate against MRSA,with the average diameter of inhibition zone of 37.7 mm.The antibacterial activity of pigment-producing strains was better than that of non-pigment producing strains.Conclusion The antibacterial material of Pseudomonas aeruginosa has strong antibacterial activity against the 32 strains of MRSA.This finding,which is the first reported in Chine,will pave a new way for the development of antibacterial drugs against MRSA infection.