Follow up study on dynamic change in marks of HBV infection in occupational population

Objective To understand the dynamic change in marks of HBV in infected persons. Methods A follow up study. Results The positive rate of HBsAg was 14.83% (354/2 387) in 1995, 14.84% (268/1 086) in 1996, 12.03% (323/2 685) in 1997. The positive rate of anti HBs was 1.22%(29/2 387), and annual negative returning rate of anti HBs was 24.92%. The positive rate of HBeAg in HBV carriers was 15.04%, and negative returning rate of HBeAg was 78.27%. There was cohort effectiveness in the process of dynamic change in HBV infection. There were ten models of HBV infection. It was the commonest model that anti HBs, anti HBc, and anti HBe emerged simultaneously, and it accounted for 46.05% of total infected persons. Only one kind of mark of HBV infection accounted for 30.79%. Conclusions After people are infected by HBV, the marks of HBV infection vary. Negative returning of marks of HBV infection seldom occures in HBV carrier. The results indicate that people who are infected by HBV could carry the marks of HBV infection for a long time, even throughout their life.