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2006•Chinese Journal of Clinical Oncology and RehabilitationRequires access

Efficacy of azasetron hydrochloride in the treatment of nausea and vomiting induced by chemotherapy

Yang Sheng-feng

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Abstract

Objective To evaluate the efficacy of azastron hydrochloride in prevention of naesea and vomiting caused by cancer chemotherapy.Method Fifty-two patients were randomized to treament group(26 cases) and control group(26 cases).Results The rates of nausea-free were 96.2% and 92.3%,the rates of vomiting-free were 100% and 88.5%,and the rates of constipation were 42.3% and 57.7% in azastron and ondansetron groups respectively.Conclusion Azastron is effective in treatment of nausea and vomiting induced by chemotherapy,and its side effects are mild.

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Objective To evaluate the efficacy of azastron hydrochloride in prevention of naesea and vomiting caused by cancer chemotherapy.Method Fifty-two patients were randomized to treament group(26 cases) and control group(26 cases).Results The rates of nausea-free were 96.2% and 92.3%,the rates of vomiting-free were 100% and 88.5%,and the rates of constipation were 42.3% and 57.7% in azastron and ondansetron groups respectively.Conclusion Azastron is effective in treatment of nausea and vomiting induced by chemotherapy,and its side effects are mild.

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Available abstract

Objective To evaluate the efficacy of azastron hydrochloride in prevention of naesea and vomiting caused by cancer chemotherapy.Method Fifty-two patients were randomized to treament group(26 cases) and control group(26 cases).Results The rates of nausea-free were 96.2% and 92.3%,the rates of vomiting-free were 100% and 88.5%,and the rates of constipation were 42.3% and 57.7% in azastron and ondansetron groups respectively.Conclusion Azastron is effective in treatment of nausea and vomiting induced by chemotherapy,and its side effects are mild.

Key concepts: Vomiting, Nausea, Medicine, Chemotherapy, Anesthesia, Ondansetron, Constipation, Side effect (computer science)

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