2012Xiandai shengwu yixue jinzhanRequires access

Biological Characteristics of Endothelial Progenitor Cells and Its Advancement

Bikui Zhang

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Abstract

Endothelial progenitor cells(EPCs) are precursors of endothelial cells,which are able to differentiate into mature endothelial cells.Studies are needed to increase more detailed understanding on the mechanisms of EPCs differentiation,survival,homing and distribution of the tissue.The human EPCs has potential to be used as diagnostic and prognostic or therapeutic tools in the future.This paper reviewed the biological characteristics and its advancement of EPCs,which including separation,culture and iden-tification,surface marker,mobilization,differentiation and homing.

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What this paper is about

Endothelial progenitor cells(EPCs) are precursors of endothelial cells,which are able to differentiate into mature endothelial cells.Studies are needed to increase more detailed understanding on the mechanisms of EPCs differentiation,survival,homing and distribution of the tissue.The human EPCs has potential to be used as diagnostic and prognostic or therapeutic tools in the future.This paper reviewed the biological characteristics and its advancement of EPCs,which including separation,culture and iden-tification,surface marker,mobilization,differentiation and homing.

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Available abstract

Endothelial progenitor cells(EPCs) are precursors of endothelial cells,which are able to differentiate into mature endothelial cells.Studies are needed to increase more detailed understanding on the mechanisms of EPCs differentiation,survival,homing and distribution of the tissue.The human EPCs has potential to be used as diagnostic and prognostic or therapeutic tools in the future.This paper reviewed the biological characteristics and its advancement of EPCs,which including separation,culture and iden-tification,surface marker,mobilization,differentiation and homing.

Key concepts: Homing (biology), Progenitor cell, Progenitor, Endothelial stem cell, Cell biology, Stem cell, Immunology, Medicine

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