2007Fudan xuebao. Yixue banRequires access

Biological characteristics of endothelial progenitor cells

Bing Jia

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Abstract

Endothelial progenitor cells(EPCs) ,as a subtype of progenitor cells, have the capacity to differentiate into mature endothelial cells in vitro and in vivo. Currently, EPCs have been identified in adult peripheral blood, bone marrow, and human umbilical cord blood. This review summarized recent advances in the characterization of EPCs,and discussed potential utility of EPCs in cardiovascular diseases.

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What this paper is about

Endothelial progenitor cells(EPCs) ,as a subtype of progenitor cells, have the capacity to differentiate into mature endothelial cells in vitro and in vivo. Currently, EPCs have been identified in adult peripheral blood, bone marrow, and human umbilical cord blood. This review summarized recent advances in the characterization of EPCs,and discussed potential utility of EPCs in cardiovascular diseases.

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Available abstract

Endothelial progenitor cells(EPCs) ,as a subtype of progenitor cells, have the capacity to differentiate into mature endothelial cells in vitro and in vivo. Currently, EPCs have been identified in adult peripheral blood, bone marrow, and human umbilical cord blood. This review summarized recent advances in the characterization of EPCs,and discussed potential utility of EPCs in cardiovascular diseases.

Key concepts: Progenitor cell, Umbilical cord, Progenitor, Bone marrow, Endothelial progenitor cell, Stem cell, Immunology, Endothelial stem cell

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