A Clinical Study on the Minor Myocardial Injury Associated with Percutaneous Coronary Intervention

Objective To investigate the change of the myocardial injury marker before and after percutaneous coronary intervention (PCI). Methods The patients enrolled in this study were divided into two groups. In PCI group, 26 patients underwent PCI. In control group, 30 patients only underwent coronary arteriography(CAG). The levels of serum CK-MB and cTnI were measured before and 16h after PCI. Results In PCI group, serum cTnI levels were 1 01±0 63ng/ml and 1 75±1 73ng/ml before and after PCI respectively, the difference of which was significant(P0 05). And serum CK-MB levels before and after PCI were 14 27±5U/L and 15 92±9 18U/L respectively, the diference of which was not significant(P0 05). In control group, serum cTnI levels were 0 8±0 16ng/ml and 0 87±0 26ng/ml before and after CAG, the difference of which was not significant(P0 05). And serum CK-MB levels before and after CAG were 13 53±6 68U/L and 14 27±7 36U/L respectively, the difference of which was not significant(P0 05). In PCI group,the balloon inflation time, the highest inflation pressure and the number of placed stents in the patients with the increased level of cTnI had not significant difference compared with those in the patients without the increased level of cTnI. There were 2 patients with side branch occlusion, whose cTnI level obviously elevated. Conclusion PCI could lead to minor myocardial injury in some patients, the reason of which might be side branch occlusion. The number of placed stents and balloon inflation time were not associated with the minor myocardial injury.