Minor myocardial injury and it's clinical effects after percutaneous transluminal coronary angioplasty with or without stenting

Objective:To investigate the minor myocardial injury and it's clinical effects after successful percutaneous transluminal coronary angioplasty(PTCA) with or without stenting. Methods:Eighty-three patients with stable angina and received uncomplicated PTCA or stenting to single vessel disease were selected. Serum levels of cardiac troponin I (cTnI) and CK-MB were measured before, 6, 12, 24 and 48 h after procedure. Echocardiogram were done to test LVEF during 4 to 5 weeks follow-up, and compared with the baseline before the procedure. All cardiac events were recorded during the follow-up periods.Results:Abnormal values of cTnI and(or) CK-MB were observed in 23 patients, 21 after stenting and 2 after PTCA alone. The frequency of abnormal cTnI levels was significantly higher than that of CK-MB after the procedure ( 24.1% vs 6.0%; P 0.01). In injury group with abnormal cTnI and/or CK-MB, total time of inflation and maximum time of each inflation were longer than non-injury group of normal cTnI and/or CK-MB levels (P 0.05 and P 0.01), but there were no significant difference of times of inflation and maximum pressure between two groups(P 0.05). The rate of side-branch occlusion was also higher in injury group ( 56.5% vs 18.3%; P 0.01). Cardiac events occurred in 1 patient( 4.3%) of injury group compared with 4 patients ( 6.4%) of non-injury group (P 0.05), and the changes of LVEF were almost same in two groups during follow-up.Conclusion:Minor myocardial injury is more common after stenting than PTCA alone. But there was no significant bad effect on the recent prognosis after this kind of injury.