The Clinical Value of Coronary Artery Stenosis Diagnosed by 256-Slice Computed Tomographic Angiography

Objective To evaluate and analyze the diagnostic accuracy of 256-slice computed topographic angiography(CTA) and coronary angiography(CAG) in patients with coronary artery disease(CAD). Methods One hundred and one patients(suspected CAD and confirmed CAD with re-examination) underwent the 256-slice CTA and CAG were included in this study. The coronary artery imaging data of 101 patients were retrospectively collected and analyzed. Calculations for accuracy were conducted on a segmental basis. A total of 1 313 comparable segments were evaluated. The accuracy of 256-slice CTA was evaluated in the diagnosis of moderate and severe stenosis of coronary artery(stenosis in segments of coronary artery≥50%). The values for diagnostic accuracy of 256-slice CTA were analyzed, including mild stenosis: 50%, moderate stenosis: 50%～75%, severe stenosis: 76%～100% and complete occlusion. Results The sensitivity of 256-slice CTA for diagnostic accuracy to coronary heart disease was 94.87%, and the specificity was 52.17%. The positive predictive value was 87.06% and the negative predictive value was 75.00%. The accuracy rates of 256-slice CTA for evaluating the coronary artery stenosis were: mild stenosis(44.23%), moderate stenosis(44.23%), severe stenosis(40.00%) and total occlusion of coronary artery(51.77%), respectively. Conclusion The diagnostic value of 256-slice CTA for the degree of coronary artery stenosis is insufficient, which can be used as a potential alternative screening examination to detect coronary artery stenosis in suspected patients and a method of re-examination in low risk patients with CAD.