ANTIOXIDANT AND FREE RADICAL SCAVENGING ACTIVITIES OF DOLICHANDRONE ATROVIRENS USING VARIOUS IN VITRO ASSAY MODELS

In the present study, the antioxidant and free radical scavenging activities of methanolic leaf and bark extracts of Dolichandrone atrovirens was evaluated by different in vitro antioxidant assay models. The total phenol and flavonoid content was also determined in the extracts. The plant extracts exhibited strong antioxidant and radical scavenging activity on ABTS radical cation, DPPH free radical, hydrogen peroxide, superoxide radical and hydroxyl radical. Both extracts showed strong activity in total reducing power assay. The antioxidant and free radical scavenging activities of the extracts were comparable to standard antioxidants used such as ascorbic acid and rutin. The extracts had good phenol and flavonoid contents. The antioxidant and radical scavenging activity of the plant extracts may be due to the rich amount of phenols and flavonoids. Therefore, the plant could be considered as a very good antioxidant source with therapeutic potential.