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ATIOXIDAT POTETIAL OF IDIGOFERA LIAEI ALI. - AIVITRO STUDY.

Senthil Kumar Raju, Rajkapoor Balasubramanian, Parthasarathi Perumal

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Abstract

Summary In the present study, the antioxidant activity of methanol extract of Indigofera linnaei (MEIL) was evaluated by different in vitro antioxidant assay models. The total phenol and flavonoid content was also determined in the extract. MEIL exhibited strong antioxidant and scavenging activity on ABTS radical cation, DPPH free radical, hydrogen peroxide, nitric oxide, superoxide radical and hydroxyl radical. The extract showed strong activity in Iron reducing power assay. The antioxidant and free radical scavenging activities of the extract were comparable to standard antioxidants used such as ascorbic acid and rutin. The extract had good phenol and flavonoid contents. The antioxidant activity may be due to the rich amount of phenols and flavonoids present in the extract. Therefore, the plant could be considered as a very good antioxidant source with therapeutic potential.

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Summary In the present study, the antioxidant activity of methanol extract of Indigofera linnaei (MEIL) was evaluated by different in vitro antioxidant assay models. The total phenol and flavonoid content was also determined in the extract. MEIL exhibited strong antioxidant and scavenging activity on ABTS radical cation, DPPH free radical, hydrogen peroxide, nitric oxide, superoxide radical and hydroxyl radical. The extract showed strong activity in Iron reducing power assay. The antioxidant and free radical scavenging activities of the extract were comparable to standard antioxidants used such as ascorbic acid and rutin. The extract had good phenol and flavonoid contents. The antioxidant activity may be due to the rich amount of phenols and flavonoids present in the extract. Therefore, the plant could be considered as a very good antioxidant source with therapeutic potential.

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Available abstract

Summary In the present study, the antioxidant activity of methanol extract of Indigofera linnaei (MEIL) was evaluated by different in vitro antioxidant assay models. The total phenol and flavonoid content was also determined in the extract. MEIL exhibited strong antioxidant and scavenging activity on ABTS radical cation, DPPH free radical, hydrogen peroxide, nitric oxide, superoxide radical and hydroxyl radical. The extract showed strong activity in Iron reducing power assay. The antioxidant and free radical scavenging activities of the extract were comparable to standard antioxidants used such as ascorbic acid and rutin. The extract had good phenol and flavonoid contents. The antioxidant activity may be due to the rich amount of phenols and flavonoids present in the extract. Therefore, the plant could be considered as a very good antioxidant source with therapeutic potential.

Key concepts: Chemistry, Antioxidant, Rutin, DPPH, ABTS, Flavonoid, Ascorbic acid, Hydroxyl radical

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