The experimental study of splenic embolization before laparoscopic megasplenectomy

Objective:To assess the value of splenic arterial embolization before laparoscopic megasplenectomy and the difference of two ways of splenic embolization.Methods:Ten healthy dogs were randomly divided into 2 groups: group A(splenic arterial trunk embolization,n=5) and group B(total splenic embolization,n=5).After establishing animals model of megalosplenia,we respectively used gelatin sponge stripe and powder to perform splenic embolization.Then observed the variation of splenic pathohistology before embolization and 1 hour,1 day,7 day,14 day,28 day after splenic embolization.Results:There were no morbidity and mortality in both groups.The size and pathological change of spleen of two group of animals were different after embolization.Conclusions:It is feasible and safe for two methods to be used to embolize the megalosplenia before laparoscopy.These two ways do cut down the difficulty of operation and reduce the bleeding in the process of laparoscopic surgery.