2014•Journal of Clinical Pulmonary MedicineRequires access
Detection of VEGF in pleural fluid of patients with lung cancer and its clinical significance
Zhang Lin
Open publisher page 0 citations
Abstract
Objective To explore the significance of VEGF levels in pleural effusion of patients with lung cancer and clinical significance. Methods 70 patients with pleural effusion were selected in our hospital. The difference in VEGF and the positive expression were observed and analyzed. Results The level of VEGF was higher in patients with malignant pleural effusion than benign pleural( P 0. 05). The best level of VEGF in pleural fluid for the diagnosis of malignant pleural effusion was 1732. 65pg / ml. The positive expression rate of VEGF in malignant pleural effusion was 86. 11%,which was obviously higher than that in benign pleural effusion( 26. 47%)( χ2=25. 40,P 0. 05). There was no significant difference in VEGF among different histological types( P 0. 05).Conclusion The detection of VEGF in pleural effusion of patients with lung cancer has certain clinical diagnostic value.