Non-invasive Positive Pressure Ventilation in Treatment of Acute Exacerbation of COPD with Type II Respiratory Failure

Objective To study the clinical effect of non-invasive positive pressure ventilation(NIPPV) of chronic obstructive pulmonary disease(COPD) with type II respiratory failure.Methods To observe the data of arterial blood gas(pH,PaO_2,PaCO_2),the course of disease in hospital,the rate of endotracheal intubation,the mortality of the 68 patients in NIPPV (33 cases) and compare with those of patients(35 cases) without NIPPV treatment.Results The data of 33 cases in arterial blood gas had been improved significantly after NIPPV,the course of disease in hospital was significantly shorter and the rate of endotracheal intubation and mortality of the patients was significantly lower in NIPPV than those in no NIPPV.There was remarkably difference between two groups.Conclusion NIPPV is an effective method in the treatment of acute exacerbation of COPD with type II respiratory failure.NIPPV can delay the course of disease if it is applied in early stage.