The experimental study of optimizing the iodinated contrast media dose in MSCT Angiography of Pulmonary arter

【Objective】 To Discuss the feasibility of reducing the iodine contrast media dose in MSCT Angiography of Pulmonary artery(MSCTPA).【Methods】 Three groups of different iodinated contrast media doses(A-1.50ml/kg,B-1.25ml/kg,C-1.00ml/kg) were random injected with 1.5 m/s rate into 3 dogs 8 times respectively,A total of 24 times of Pulmonary artery CT Angiography Scanning.According to the source images and the VR,MIP,MPR images,the result of each scan was respectively graded by the sharpness of the edge,Pulmonary artery branch conditions and Pulmonary vein conditions.【Results】 The results of the three groups were correlative well,the Kappa values were respectively 0.84,0.87,0.81.There were no statistical differences between every two groups.【Conclusion】 It is feasible to obtain excellent canine pulmonary CTA images by reducing the contrast media dose in MSCTPA,provide the experimental basis for optimization of iodinated contrast media dose and reducing the toxic side effect.