Feasibility of multislice CT angiography of pulmonary artery with high concentration and low dose contrast media

Objective:To study the feasibility of multislice CT angiography of pulmonary artery with high concentration and low dose contrast media.Methods:Forty patients with chest dynamic enhanced using multislice CT body-perfusion protocol were divided into 2 groups according to the kind and dosage of contrast media as follows: Group A,300 mgI/ml contrast media 100 ml and saline 30 ml;Group B,400 mgI/ml contrast media 60 ml and saline 30 ml.Injected rate was 4 ml/s.The time-density curve(TDC) of the trunk of pulmonary artery was delineated.The time to peak,peak contrast enhancement,the time of begin to 200 HU(Tb200) and the time of duration on 200HU(T200) were recorded.Results:As for the time to peak and peak contrast enhancement of the trunk of pulmonary artery,group B was earlier and higher than group A.The T200 and Tb200 had significant difference between the two groups.Conclusion:It is feasible to use high concentration and low dose contrast media for multislice CT pulmonary artery angiography.