2010•Guide of China MedicineRequires access

The Influence and Efficacy about Intravenous Thrombolytic Therapy for Acute Cerebral Infarction on Hemorheology by Urokinase

Wang Ying-huo

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Abstract

Objective To observe the effect about urokinase(UK) thrombolytic therapy in acute cerebral infarction and the influence on hemorheology.Methods Within the 6 ~ 24h 72 cases of acute cerebral infarction were randomly divided into 3 groups,the incidence of which 20 cases within 6 ~ 12h for treatment A group,incidence of 12 ~ 24h in 22 cases for the treatment of B group,and control group(C group,30 cases),the two treatment groups were urokinase 1,000,000 ~ 2,000,000 U intravenous drip after the application of conventional treatment,the control group received conventional therapy.Results The treatment group used the total effective intravenous thrombolysis,the degree of neurological deficit on the resumption,the improvement of blood rheology was significantly better than the control group(P0.05),but the two treatment groups no significant difference(P0.05).Conclusion Urokinase intravenous thrombolysis within 6 ~ 24h no contraindications thrombolysis on acute cerebral infarction is safe,effective,and can significantly change blood rheology.

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Objective To observe the effect about urokinase(UK) thrombolytic therapy in acute cerebral infarction and the influence on hemorheology.Methods Within the 6 ~ 24h 72 cases of acute cerebral infarction were randomly divided into 3 groups,the incidence of which 20 cases within 6 ~ 12h for treatment A group,incidence of 12 ~ 24h in 22 cases for the treatment of B group,and control group(C group,30 cases),the two treatment groups were urokinase 1,000,000 ~ 2,000,000 U intravenous drip after the application of conventional treatment,the control group received conventional therapy.Results The treatment group used the total effective intravenous thrombolysis,the degree of neurological deficit on the resumption,the improvement of blood rheology was significantly better than the control group(P0.05),but the two treatment groups no significant difference(P0.05).Conclusion Urokinase intravenous thrombolysis within 6 ~ 24h no contraindications thrombolysis on acute cerebral infarction is safe,effective,and can significantly change blood rheology.

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Available abstract

Objective To observe the effect about urokinase(UK) thrombolytic therapy in acute cerebral infarction and the influence on hemorheology.Methods Within the 6 ~ 24h 72 cases of acute cerebral infarction were randomly divided into 3 groups,the incidence of which 20 cases within 6 ~ 12h for treatment A group,incidence of 12 ~ 24h in 22 cases for the treatment of B group,and control group(C group,30 cases),the two treatment groups were urokinase 1,000,000 ~ 2,000,000 U intravenous drip after the application of conventional treatment,the control group received conventional therapy.Results The treatment group used the total effective intravenous thrombolysis,the degree of neurological deficit on the resumption,the improvement of blood rheology was significantly better than the control group(P0.05),but the two treatment groups no significant difference(P0.05).Conclusion Urokinase intravenous thrombolysis within 6 ~ 24h no contraindications thrombolysis on acute cerebral infarction is safe,effective,and can significantly change blood rheology.

Key concepts: Medicine, Urokinase, Thrombolysis, Hemorheology, Incidence (geometry), Cerebral infarction, Anesthesia, Surgery

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