An Experimental Study of Lung Transplantation

Objective To observe the function of transplanted lung and postoperative restoration in experimental animals. Methods Four left lung autotransplantation and four left lung allotransplantation were performed on dogs and cows. Results After transplantation, the functions of ventilation and gas transfer in the transplanted lung were normal. The animals restored spontaneous respiration. The dogs could stand up and walk. Conclusion This experimental methods provide an operative procedure of lung transplantation on animal, and could be a preparatory step for further clinical lung transplantation practice.