Mycoplasma infection status in urogenital tract and drug susceptibility analysis

Objective To understand the status of mycoplasma infection and drug susceptibility in the Shilong region and to provide reference basis for clinical rational drug use.Methods The reagents kits produced by Zhuhai Yimin bioengineering enterprise were adopted to perform mycoplasma culture,identification and susceptibility testing.Results Among 1 730 specimens,840 cases of mycoplasma infection were detected with the total detection rate of 48.6%,including Ureaplasma urealyticum(Uu) infection in 741 cases(42.8%),Mycoplasma hominis(Mh) infection in 10 cases(0.6%) and Uu+Mh infection in 89 cases(5.1%).The detection rate was 20.5% in males and 51.4% in females,females′ were obviously higher than males′.The results of dug susceptibility tests showed that simple Uu infection had higher sensitivity(90%) to josamycin,doxycycline and clarithromycin,simple Mh infection had the sensitivity(80%) to josamycin and doxycycline,and Uu+Mh infection were relatively sensitive to josamycin and doxycycline( 75%).Conclusion Mycoplasma infection in Shilong region is dominated by Uu infection.Josamycin,doxycycline and clarithromycin can be used as empirical medication to treat mycoplasma infections in theis region.But before clinical treatment,the mycoplasma culture and drug susceptibility tests should be performed as possible for rational and standardized medication.