Status of mycoplasma infection in urogenital tract and drug sensitivity analysis

Objective To find out the epidemiological situation of mycoplasma infection in men and women in Changsha and to establish the drug sensitivity spectrum of mycoplasma in native area to provide reference for rational clinical drug use.Methods The urinary tract(cervix) secretion samples from 1 947 cases of genitourinary infection were performed the culture,identification and drug sensitivity test for Uu and Mh by using mycoplasma kit.Results In 1 947 suspected cases,mycoplasma positive was in 805 cases with the positive rate of 41.4%.The highest detection rate was in Uu(22.6%);followed by Uu + Mh mixed infection with the detection rate of 14.0%;Mh infection was the lowest just 4.8%.From a gender perspective,the positive rate was 24.5% in male and 44.0% in female,the infection rate of females was significantly higher than that of males.The drug susceptibility results showed that josamycin,doxycycline and minocycline had the higher antimicrobial activity on mycoplasma,while the highest resistance to erythromycin was highest and most common.Conclusion Mycoplasma infection in Changsha area is mainly Ureaplasma urealyticum(Uu) infection,Uu + Mh mixed infection is also increasing year by year.Mycoplasma(Uu,Mh,Uu + Mh) in male and female urogenital tract infections is close to common antibiotic susceptibility spectrum.Josamycin,minocycline and doxycycline can be used as the first choice of antibiotics in the empirical treatment of mycoplasma infections in this region.