2013Unpublished venueRequires access

Clinical efficacy of Wuchong Tongluo capsules combined with Western medicines in treatment of diabetic peripheral neuropathy:a report of 60 cases

You Xiao-li

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Abstract

Objective:To observe the clinical efficacy of Wuchong Tongluo capsules combined with Western medicines in the treatment of diabetic peripheral neuropathy(DPN).Methods:A total of 120 patients with DPN were randomly divided into treatment group(n = 60) and control group(n = 60).Both groups received conventional treatment to have blood glucose levels controlled within a desirable range,as well as vitamin B1 tablets,mecobalamin capsules,and epalrestat tablets,and the treatment group was given Wuchong Tongluo capsules as an addition.Results:The treatment group had a significantly higher overall response rate than the control group(91.67% vs 71.67%,P 0.01).The treatment group had a significantly more improvement in total Toronto score than the control group(P 0.05).There was also significant difference in nerve conduction velocity between the treatment group and control group(P 0.01).No adverse events were seen in either group.Conclusion:Wuchong Tongluo capsules combined with Western medicines have a satisfactory clinical effect and cause no adverse events in the treatment of DPN.

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Objective:To observe the clinical efficacy of Wuchong Tongluo capsules combined with Western medicines in the treatment of diabetic peripheral neuropathy(DPN).Methods:A total of 120 patients with DPN were randomly divided into treatment group(n = 60) and control group(n = 60).Both groups received conventional treatment to have blood glucose levels controlled within a desirable range,as well as vitamin B1 tablets,mecobalamin capsules,and epalrestat tablets,and the treatment group was given Wuchong Tongluo capsules as an addition.Results:The treatment group had a significantly higher overall response rate than the control group(91.67% vs 71.67%,P 0.01).The treatment group had a significantly more improvement in total Toronto score than the control group(P 0.05).There was also significant difference in nerve conduction velocity between the treatment group and control group(P 0.01).No adverse events were seen in either group.Conclusion:Wuchong Tongluo capsules combined with Western medicines have a satisfactory clinical effect and cause no adverse events in the treatment of DPN.

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Available abstract

Objective:To observe the clinical efficacy of Wuchong Tongluo capsules combined with Western medicines in the treatment of diabetic peripheral neuropathy(DPN).Methods:A total of 120 patients with DPN were randomly divided into treatment group(n = 60) and control group(n = 60).Both groups received conventional treatment to have blood glucose levels controlled within a desirable range,as well as vitamin B1 tablets,mecobalamin capsules,and epalrestat tablets,and the treatment group was given Wuchong Tongluo capsules as an addition.Results:The treatment group had a significantly higher overall response rate than the control group(91.67% vs 71.67%,P 0.01).The treatment group had a significantly more improvement in total Toronto score than the control group(P 0.05).There was also significant difference in nerve conduction velocity between the treatment group and control group(P 0.01).No adverse events were seen in either group.Conclusion:Wuchong Tongluo capsules combined with Western medicines have a satisfactory clinical effect and cause no adverse events in the treatment of DPN.

Key concepts: Medicine, Peripheral neuropathy, Adverse effect, Clinical efficacy, Western medicine, Nerve conduction velocity, Treatment and control groups, Internal medicine

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