An influence on oxidative stress injury from Chinese rose pigment to motion rat skeletal muscle

Objective: Observe the influence on oxidative stress injury from Chinese rose pigment to motion rat skeletal muscle and discuss on the mechanism of action.Methods: 40 male SD rats randomly divided into control group(CG),exercise group(EG0h,EG48h),exercise and tonic group(ER0h,ER48h),every group has 8 rats.EG and ER groups were trained with increasing load of treadmill running for 4weeks,ER group gave Chinese rose pigment 1ml/100g intragastric administration for everyday.After training according the group draw materials,determine the activity of serum CK and LDH,the activity of MDA and SOD in muscular tissues.Results:(1)After exercise the activity of serum CK and LDH on ER group increases marked(P0.05),48h after exercise still overtops CG group(P0.05);48h after exercise the activity of serum CK and LDH on ER group clearly blow EG group(P 0.05).(2)EG group after exercise,the MDA of muscular tissues significantly increased(P0.05),the activity of SOD significantly reduced(P0.05);ER group after exercise and 48h after exercise,the MDA of muscular tissues significantly reduce EG group(P0.05),the SOD activity overtops EG group immediately and after 48h group(P0.05).Conclusion: supplement Chinese rose pigment can significantly inhibite the lipid per-oxidation of exercise muscle tissue,reduce the activity of serum muscle enzymes,so Chinese rose pigment has the inhibition effect of moving oxidative stress injury.