Morning Blood Pressure Surge Associates with Carotid Atherosclerosis

Objective To investigate the association between morning blood pressure surge(MBPS)and the ambulatory blood pressure monitoring parameters on carotid artery intima-media thickness(IMT)in hypertensive patients.Methods Based on the occurrence of MBPS two hundred twenty six hypertensive patients were allocated as MBPS(n=51)or non-MBPS(n=175).However,based on the IMT,226 patients were stratified as IMT increased(n=94)or group normal IMT(n=132).Plasma lipids,24 h ambulatory blood pressure monitoring(ABPM)and ultrasound examinations of the IMT of carotid arteries were determined.Results 1)The value of MBPS,mean arterial pressure(MAP),morning pulse pressure(MPP),carotid artery IMT,carotid artery crouse score in MBPS group were significantly higher than that in no MBPS groups(P0.05).2)The value of MBPS,morning MAP,MPP,24 h MSBP,24 h MDBP,d MSBP,d MDBP,n MSBP and n MDBP in IMT increased group were higher than those in group normal IMT(P0.05).Conclusion There were more severe carotid atherosclerosis in the MBPS patients than that in no MBPS patients.Morning blood pressure surge was associated with the progress of carotid atherosclerosis.