2013Journal of Clinical Pulmonary MedicineRequires access

Clinical observation of lung protective ventilation strategy in the treatment of elderly patients with severe pneumonia

Yan Ju

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Abstract

Objective To explore the clinical efficacy and safety of lung protective ventilation in the treatment of elderly patients with severe pneumonia. Methods 96 elderly patients with severe pneumonia from September 2010 to January 2013 were randomly divided into two groups. The group A(50 cases) was treated with protective mechanical ventilation group with the tidal volume of 6 to 8 ml /kg,and the group B was treated with common mechanical ventilation with the tidal volume of 8 to 12 ml / kg. A comparison was made upon arterial blood gas analysis of PaO2,PaCO2,oxygenation index between the two groups,as well as upon duration of hospital stay and extubation,mortality and efficiency. Results The duration of hospital stay and extubation was obviously shorter in the group A than in the group B with statistical significance( P 0. 05). The improvement of PaO2,PaCO2 and oxygenation index was more pronounced in the group A than in the group B( P 0. 05). Conclusion Mechanical lung protective ventilation is safe and effective in the treatment of elderly patients with severe pneumonia,which can improve their oxygenation.

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Objective To explore the clinical efficacy and safety of lung protective ventilation in the treatment of elderly patients with severe pneumonia. Methods 96 elderly patients with severe pneumonia from September 2010 to January 2013 were randomly divided into two groups. The group A(50 cases) was treated with protective mechanical ventilation group with the tidal volume of 6 to 8 ml /kg,and the group B was treated with common mechanical ventilation with the tidal volume of 8 to 12 ml / kg. A comparison was made upon arterial blood gas analysis of PaO2,PaCO2,oxygenation index between the two groups,as well as upon duration of hospital stay and extubation,mortality and efficiency. Results The duration of hospital stay and extubation was obviously shorter in the group A than in the group B with statistical significance( P 0. 05). The improvement of PaO2,PaCO2 and oxygenation index was more pronounced in the group A than in the group B( P 0. 05). Conclusion Mechanical lung protective ventilation is safe and effective in the treatment of elderly patients with severe pneumonia,which can improve their oxygenation.

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Available abstract

Objective To explore the clinical efficacy and safety of lung protective ventilation in the treatment of elderly patients with severe pneumonia. Methods 96 elderly patients with severe pneumonia from September 2010 to January 2013 were randomly divided into two groups. The group A(50 cases) was treated with protective mechanical ventilation group with the tidal volume of 6 to 8 ml /kg,and the group B was treated with common mechanical ventilation with the tidal volume of 8 to 12 ml / kg. A comparison was made upon arterial blood gas analysis of PaO2,PaCO2,oxygenation index between the two groups,as well as upon duration of hospital stay and extubation,mortality and efficiency. Results The duration of hospital stay and extubation was obviously shorter in the group A than in the group B with statistical significance( P 0. 05). The improvement of PaO2,PaCO2 and oxygenation index was more pronounced in the group A than in the group B( P 0. 05). Conclusion Mechanical lung protective ventilation is safe and effective in the treatment of elderly patients with severe pneumonia,which can improve their oxygenation.

Key concepts: Medicine, Mechanical ventilation, Oxygenation index, Pneumonia, Oxygenation, Ventilation (architecture), Anesthesia, Tidal volume

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