Clinical Observation of Efficiency of Tongxinluo Capsule in 50 Patients with Cerebral Infarction

Objective To observe the influence of Tongxinluo capsule on clinical neurological functional deficit scores(NFDS),clinical effect,blood-lipid,carotid atherosclerotic plaque and carotid stenosis in patients with cerebral infarction.Methods One hundred and six cases of cerebral infarction combined with carotid atherosclerosis were randomly divided into treating group and control group.4 Tongxinluo capsules were orally administered(t.i.d) on the basis of conventional therapy for 3 months in the treating group,and control group was treated with conventional therapy only.Changes of NFDS,carotid atherosclerotic plaque,blood-lipid,carotid stenosis in both groups were observed before and after treatment 1 months and 3 months.Results NFDS decreased 1 month and 3 months after the treatment in both groups as compared with those before treatment,the difference was significantly(P0.01);at the same time,compared with the control group,NFDS in treatment group reduced obviously after 1 month and 3 months(P0.01);the efficiency and total efficiency in treatment group were improved as compared with the control group,the difference was significant(P0.01).The blood lipids in the treatment group were significantly decreased after 1 month and 3 months(P0.05),and were lower than that in the control group(P0.01).The number and size of carotid atherosclerosis plaque in control group showed no significant changes after the treatment(P0.05),but in the treatment group showed significant changes,and the plaques were much smaller than the control group(P0.05).Conclusion Tongxinluo capsule has the effects of reducing neurological deficit scores,lowering lipid levels,reducing the size and numbers of carotid atherosclerosis plaque.It can improve the clinical efficacy in patients with cerebral infarction obviously.