2011•Zhongguo yaofangRequires access

Therapeutic Efficacy of Reduced Glutathione Combined with Magnesium Isoglycyrrhizinate for Alcoholic Liver Disease

Jia Minghua

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Abstract

OBJECTIVE:To observe the clinical efficacy of oral dose of reduced glutathione combined with dripping injection of magnesium isoglycyrrhizinate for alcoholic liver disease.METHODS:A total of 60 patients with alcoholic liver disease who had been abstained from wine were randomly assigned to treatment group and control group(30 cases).Treatment group was given oral dose of reduced glutathione and intravenous dripping injection of magnesium isoglycyrrhizinate for 4 weeks.Control group was treated with intravenous dripping injection of magnesium isoglycyrrhizinate alone for 4 weeks.RESULTS:Clinical symptoms and signs,laboratory examination and B-ultrosound results were all improved in both groups,especially in the trial group.Significant differences were noted between the 2 groups(P0.05).CONCLUSION:Oral dose of reduced glutathione combined with intravenous dripping injection of magnesium isoglycyrrhizinate is safe and effective for alcoholic liver disease without obvious adverse drug reaction.

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What this paper is about

OBJECTIVE:To observe the clinical efficacy of oral dose of reduced glutathione combined with dripping injection of magnesium isoglycyrrhizinate for alcoholic liver disease.METHODS:A total of 60 patients with alcoholic liver disease who had been abstained from wine were randomly assigned to treatment group and control group(30 cases).Treatment group was given oral dose of reduced glutathione and intravenous dripping injection of magnesium isoglycyrrhizinate for 4 weeks.Control group was treated with intravenous dripping injection of magnesium isoglycyrrhizinate alone for 4 weeks.RESULTS:Clinical symptoms and signs,laboratory examination and B-ultrosound results were all improved in both groups,especially in the trial group.Significant differences were noted between the 2 groups(P0.05).CONCLUSION:Oral dose of reduced glutathione combined with intravenous dripping injection of magnesium isoglycyrrhizinate is safe and effective for alcoholic liver disease without obvious adverse drug reaction.

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Available abstract

OBJECTIVE:To observe the clinical efficacy of oral dose of reduced glutathione combined with dripping injection of magnesium isoglycyrrhizinate for alcoholic liver disease.METHODS:A total of 60 patients with alcoholic liver disease who had been abstained from wine were randomly assigned to treatment group and control group(30 cases).Treatment group was given oral dose of reduced glutathione and intravenous dripping injection of magnesium isoglycyrrhizinate for 4 weeks.Control group was treated with intravenous dripping injection of magnesium isoglycyrrhizinate alone for 4 weeks.RESULTS:Clinical symptoms and signs,laboratory examination and B-ultrosound results were all improved in both groups,especially in the trial group.Significant differences were noted between the 2 groups(P0.05).CONCLUSION:Oral dose of reduced glutathione combined with intravenous dripping injection of magnesium isoglycyrrhizinate is safe and effective for alcoholic liver disease without obvious adverse drug reaction.

Key concepts: Glutathione, Medicine, Alcoholic liver disease, Adverse effect, Gastroenterology, Oral administration, Internal medicine, Pharmacology

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