Study Advances of Cervical Neuroendocrine Tumors

Cervical neuroendocrine tumor is a rare gynecological malignancy,with the features of high malignancy,rapid progression,distant metastasis and hematogenous spread,high recurrence rate,and extremely poor prognosis.Because of its lack of specific clinical symptoms,it is difficult to differentiate from other types of cervical cancer in the early stage.High-risk HPV infection might be a major cause.Cytological abnormalities contribute to early detection,while diagnosis depends on the histopathological joint immunohistochemical examination.Effective treatment is in need,while the main treatment is still surgery,supplemented by chemotherapy combined with radiotherapy for the time being.