Analysis on the high myopic changes and related factors of functions and fundus appearances in the fellow eye of retinal detachment with different fundus impairs

Objective To observe the posterior segment changes of functions and fundus appearances in the high myopic fellow eye of retinal detachment with different fundus impairs and analyze their related factors, such as visual fields, visual electrophysiolography, and to find out the sensitive and objective methods which can detect the earlier damages to the central visual acuity in the high myopia eyes. Methods The data were divided into 11 groups, included central visual acuity, age, profession, gender, history, myopic severity, macular disturb accompanied, ocular axis, B-scan, and fundus appearances. The objective tests related to macular appearance and functions were chosen, such as LVC in the perimeter, cone-ERG, 30Hz flicker ERG, P-VEP, first order kernel in 1,2 ring of multi-focal ERG, and A/B scan , FFA/ICGA. The collected data were analyzed statistically. Results There were 94 cases with the complete data in the group divided by different fundus impairs in the high myopic fellow eye of retinal detachment. From the different constitution of the data, , the diffuse fundus impair was accompanied with myopic diopter over-10D, the age over 40 years old, and the visual acuities are lower than 0.4 ; the mean light sensitivity of 30°visual field was( 24.94±5.52)dB, lower significantly; the b wave amplitudes of 30Hz flicker response(52.03±31.46) (μV) and cone response (41.43±25.65) (μV), and M-ERG’ response density of 1 ring (76.14±50.04) (nv/deg2)and 2 ring (36.68±23.51) (nv/deg2) are significant changed, the same as b wave amplitudes of 1 ring (0.72±0.5) (μV) and 2 ring (0.51±0.31) (μV);the multiple step regression analysis, the groups of aging, visual acuity, myopic severity are positive related with the diffuse fundus damage (R=0.793). Conclusions The fundus impairs in the high myopic fellow eye of retinal detachment were being deteriorate with the aging, myopia developing, central visual acuities decreasing. We may find out the earlier, mild fundus pathologic changes according to the objective visual functional tests to prevent the blindness of high myopia.