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2006•Journal of environmental healthRequires access

Effect of Alcohol on NO Concentration in Plasma and Activity of ATP Enzyme in Erythrocytes of Rabbits

Lijuan Huang

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Abstract

Objective To explore the effects of alcohol on NO concentration in plasma and activity of ATP enzyme in erythrocytes of rabbits. Methods 32 rabbits were divided into groups and treated with alcohol, injected intravenously, at the doses of 0.5 g/kg, 1.0 g/kg and 1.5 g/kg, 15 minutes after treatment, the blood samples were collected and NO concentration in plasma, activity of ATP enzyme in erythrocytes were determined. Results NO concentration in plasma of rabbits significantly decreased in 0.5 g/kg and 1.0 g/kg groups, but increased in 1.5 g/kg group (P0.05). Activity of ATP enzyme decreased both in 1.0 g/kg and 1.5 g/kg groups (P0.05). Conclusion Alcohol may change NO concentration in plasma and decrease activity of ATP enzyme in erythrocytes of rabbits.

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Objective To explore the effects of alcohol on NO concentration in plasma and activity of ATP enzyme in erythrocytes of rabbits. Methods 32 rabbits were divided into groups and treated with alcohol, injected intravenously, at the doses of 0.5 g/kg, 1.0 g/kg and 1.5 g/kg, 15 minutes after treatment, the blood samples were collected and NO concentration in plasma, activity of ATP enzyme in erythrocytes were determined. Results NO concentration in plasma of rabbits significantly decreased in 0.5 g/kg and 1.0 g/kg groups, but increased in 1.5 g/kg group (P0.05). Activity of ATP enzyme decreased both in 1.0 g/kg and 1.5 g/kg groups (P0.05). Conclusion Alcohol may change NO concentration in plasma and decrease activity of ATP enzyme in erythrocytes of rabbits.

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Available abstract

Objective To explore the effects of alcohol on NO concentration in plasma and activity of ATP enzyme in erythrocytes of rabbits. Methods 32 rabbits were divided into groups and treated with alcohol, injected intravenously, at the doses of 0.5 g/kg, 1.0 g/kg and 1.5 g/kg, 15 minutes after treatment, the blood samples were collected and NO concentration in plasma, activity of ATP enzyme in erythrocytes were determined. Results NO concentration in plasma of rabbits significantly decreased in 0.5 g/kg and 1.0 g/kg groups, but increased in 1.5 g/kg group (P0.05). Activity of ATP enzyme decreased both in 1.0 g/kg and 1.5 g/kg groups (P0.05). Conclusion Alcohol may change NO concentration in plasma and decrease activity of ATP enzyme in erythrocytes of rabbits.

Key concepts: Alcohol, Enzyme, Enzyme assay, Chemistry, Blood plasma, Ethanol, Internal medicine, Endocrinology

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Effect of Alcohol on NO Concentration in Plasma and Activity of ATP Enzyme in Erythrocytes of Rabbits — Research Paper | ScholarLens