ScholarLens Back to search
2010•Zhōnghuá yàoxué zázhìRequires access

Preparation of Gelatin Microcapsules of Chitosan Sustained-Release and Its in Vitro Release Study

Sheng Liu

Open publisher page 0 citations

Abstract

OBJECTIVE To prepare the sustained-released microcapsules containing cimetidine with gelatin and chitosan as the basic material for the coating of microcapsules.METHODS According to the L9(34)orthogonal design,the amount of gelatin(A),chitosan(B),glutaraldehyde(C)formulas were optimized.RESULTS The factors of B,A and C showed a great effect on release rate,and the optimum formula was A2B3C1.CONCLUSION The cimetidine microcapsules with gelatin and chitosan showed good characters of relaxation.

About this research paper

What this paper is about

OBJECTIVE To prepare the sustained-released microcapsules containing cimetidine with gelatin and chitosan as the basic material for the coating of microcapsules.METHODS According to the L9(34)orthogonal design,the amount of gelatin(A),chitosan(B),glutaraldehyde(C)formulas were optimized.RESULTS The factors of B,A and C showed a great effect on release rate,and the optimum formula was A2B3C1.CONCLUSION The cimetidine microcapsules with gelatin and chitosan showed good characters of relaxation.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

OBJECTIVE To prepare the sustained-released microcapsules containing cimetidine with gelatin and chitosan as the basic material for the coating of microcapsules.METHODS According to the L9(34)orthogonal design,the amount of gelatin(A),chitosan(B),glutaraldehyde(C)formulas were optimized.RESULTS The factors of B,A and C showed a great effect on release rate,and the optimum formula was A2B3C1.CONCLUSION The cimetidine microcapsules with gelatin and chitosan showed good characters of relaxation.

Key concepts: Gelatin, Glutaraldehyde, Chitosan, Chemistry, Coacervate, Coating, Cimetidine, Chromatography

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Preparation of Gelatin Microcapsules of Chitosan Sustained-Release and Its in Vitro Release Study — Research Paper | ScholarLens