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2006•Chinese Clinical OncologyRequires access

Study the effect of antiangiogenesis of ansenic trioxide in combination with cinobufacin on chick embryo chorioallantoic membrane (CAM)

Hui-Yin Chen

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Abstract

Objective:To observe and compare the effects of antiangiogenesis in CAM between As_2O_3 and cinobufacin. Methods:One hundred living chicken embryo cultured for 7 days were divided into four groups (twenty-five pieces each group):As_2O_3 in combination with cinobufacin, cinobufacin, As_2O_3, NS control group, with methyl cellulose discs as carriers, which were incoubated together, observed their effects of angiogenesis in CAM. Results:The inhibitive effects of angiogenesis in CAM is significant among groups of As_2O_3, cinobufacin and combining group. which was the most strong for the combination drug group.Conclusion:It is a positive cooperation for As_2O_3and cinobufacin against angiogenesis in CAM, and the combination drug group is more effective in antiangiogensis in CAM.

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What this paper is about

Objective:To observe and compare the effects of antiangiogenesis in CAM between As_2O_3 and cinobufacin. Methods:One hundred living chicken embryo cultured for 7 days were divided into four groups (twenty-five pieces each group):As_2O_3 in combination with cinobufacin, cinobufacin, As_2O_3, NS control group, with methyl cellulose discs as carriers, which were incoubated together, observed their effects of angiogenesis in CAM. Results:The inhibitive effects of angiogenesis in CAM is significant among groups of As_2O_3, cinobufacin and combining group. which was the most strong for the combination drug group.Conclusion:It is a positive cooperation for As_2O_3and cinobufacin against angiogenesis in CAM, and the combination drug group is more effective in antiangiogensis in CAM.

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Available abstract

Objective:To observe and compare the effects of antiangiogenesis in CAM between As_2O_3 and cinobufacin. Methods:One hundred living chicken embryo cultured for 7 days were divided into four groups (twenty-five pieces each group):As_2O_3 in combination with cinobufacin, cinobufacin, As_2O_3, NS control group, with methyl cellulose discs as carriers, which were incoubated together, observed their effects of angiogenesis in CAM. Results:The inhibitive effects of angiogenesis in CAM is significant among groups of As_2O_3, cinobufacin and combining group. which was the most strong for the combination drug group.Conclusion:It is a positive cooperation for As_2O_3and cinobufacin against angiogenesis in CAM, and the combination drug group is more effective in antiangiogensis in CAM.

Key concepts: Chorioallantoic membrane, Angiogenesis, Embryo, Medicine, Pharmacology, Traditional medicine, Andrology, Internal medicine

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Study the effect of antiangiogenesis of ansenic trioxide in combination with cinobufacin on chick embryo chorioallantoic membrane (CAM) — Research Paper | ScholarLens