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Effect of tiopronin on liver injury caused by chemotherapy

Xin Chen

Abstract

Objective:To observe the effect of tiopronin on liver injury caused by chemotherapy.Methods:60 cancer patients suf-fered from slight liver injury after chemotherapy were randomly divided into treatment group and control group,each group 30 patients.The control group was used titamin C,titamin B6,inosine.The treatment group was used tiopronin in addition to the treatment above-mentioned.ALT,AST,TP,TBi and TBA were monitored.Results:The treatment group had significantly better effective ratio to recover the level of ALT compare with control group(P0.01).Conclusion:Tiopronin has significantly effect on recovering from hepatic injury after chemotherapy in the patients with cancer.

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Key concepts: Tiopronin, Medicine, Chemotherapy, Liver injury, Internal medicine, Gastroenterology, Oncology