Studies on Chemical Constituents of Mianyi Composite Decoction(II)

Objective:To study the chemical constituents of Mianyi composite decoction.Method:The constituents were separated and purified by column chromatography on silica gel,RP-silica gel and Sephadex LH20 from 30% alcohol elution on microporous resin chromatograph of Mianyi composite decoction.Their structures were elucidated on the basis of spectra data.Result:Eleven compounds were isolated and identified as 4-hydroxy-2(E)-nonenoic acid(1),adenine(2),quercetin(3),luteolin(4),adenosine(5),scandosidemethyl ester(6),astragaloside Ⅳ(7),galloylpaeoniflorin(8),propanoid acid(9),salvianolic acid C(10),apigenin-7-O-β-D-glucopyranoside(11).Conclusion:All of compounds were isolated from Mianyi composite decoction for the first time,and chemical type of compound 1 was isolated from single herb in Mianyi composite for the first time.