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2003•Zhongguo weishengtaixue zazhiRequires access

EFFECT OF HELICOBACTER PYLORI INFECTION ON AMMONIA CONCENTRATIONS IN PATIENTS WITH CIRRHOSIS

Yang Jing-yun

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Abstract

Objective:To study Helicobacter pylori(H.pylori)infection on ammonia concentrations in patients with cirrhosis.Methods:35 patients with cirrhosis and 25 patients with peptic uncle were measured Hp and ammonia.All the patients with H.pylori-infectde were given anti-H.pylori medications one week.After eradication therapy for H.pylori,ammonia were measured again.Results:Ammonia concentration in cirrhosis patients who were H.pylori-infected were higher than non H.pylori-infected significantly(P0.01).After eradication therapy for H.pylori,ammonia concentration in patients with cirrhosis were lower apparently(P0.05).Conclusion:Our results suggested H.pylori-infected is closely related with hyperammonemia in patientd with cirrhosis.H.pylori eradication can lower ammonia concentrations.H.pylori eradicatiog may be beneficial for therapy and prevent hyperammonemia and hepatic encephalopathy in patients with cirrhosis.

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Objective:To study Helicobacter pylori(H.pylori)infection on ammonia concentrations in patients with cirrhosis.Methods:35 patients with cirrhosis and 25 patients with peptic uncle were measured Hp and ammonia.All the patients with H.pylori-infectde were given anti-H.pylori medications one week.After eradication therapy for H.pylori,ammonia were measured again.Results:Ammonia concentration in cirrhosis patients who were H.pylori-infected were higher than non H.pylori-infected significantly(P0.01).After eradication therapy for H.pylori,ammonia concentration in patients with cirrhosis were lower apparently(P0.05).Conclusion:Our results suggested H.pylori-infected is closely related with hyperammonemia in patientd with cirrhosis.H.pylori eradication can lower ammonia concentrations.H.pylori eradicatiog may be beneficial for therapy and prevent hyperammonemia and hepatic encephalopathy in patients with cirrhosis.

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Available abstract

Objective:To study Helicobacter pylori(H.pylori)infection on ammonia concentrations in patients with cirrhosis.Methods:35 patients with cirrhosis and 25 patients with peptic uncle were measured Hp and ammonia.All the patients with H.pylori-infectde were given anti-H.pylori medications one week.After eradication therapy for H.pylori,ammonia were measured again.Results:Ammonia concentration in cirrhosis patients who were H.pylori-infected were higher than non H.pylori-infected significantly(P0.01).After eradication therapy for H.pylori,ammonia concentration in patients with cirrhosis were lower apparently(P0.05).Conclusion:Our results suggested H.pylori-infected is closely related with hyperammonemia in patientd with cirrhosis.H.pylori eradication can lower ammonia concentrations.H.pylori eradicatiog may be beneficial for therapy and prevent hyperammonemia and hepatic encephalopathy in patients with cirrhosis.

Key concepts: Cirrhosis, Hyperammonemia, Helicobacter pylori, Gastroenterology, Internal medicine, Hepatic encephalopathy, Medicine, Ammonia

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EFFECT OF HELICOBACTER PYLORI INFECTION ON AMMONIA CONCENTRATIONS IN PATIENTS WITH CIRRHOSIS — Research Paper | ScholarLens