Relationship between non-alcoholic fatty liver disease and metabolic syndrome in adults

Objective To explore the relationship between non-alcoholic fatty liver disease(NAFLD)and metabolic syndrome(MS).Methods A cross-sectional survey was performed in 3774 adults aged over 20 Questionaire,physical examination,fasting plasma glucose,serum lipid-profile,alanine aminotransferase,blood uric acid and abdominal ultrasonographic examination were undertaken.Results(1)The prevalence of NAFLD and MS was 23.5% and 22.8%,respectively.The prevalence of NAFLD with MS was 12.6%.(2)Compared with the normal group,the risk for fatty liver was increased by more than 13 fold in MS group,central obesity group,raised blood pressure group,raised fasting glucose group,raised triglyceride group,or reduced high density lipoprotein-cholesterol group.(3)The consistency of two different MS definitions was high before and after any component of MS was replaced by NAFLD(all Kappa value:0.53～0.89,P0.01).(4)Multifactor Logistic analysis showed that NAFLD and MS were independently ralated after adjusting sex,age and many metabolic components(OR 2.342,95% CI:1.825～3.007;P0.01).Conclusion There is a high prevalence of NAFLD and MS in adults from an enterprise in Changsha;NAFLD is closely related to the metabolic syndrome;NAFLD may be considered as a component of MS.