2014Xiandai shengwu yixue jinzhanRequires access

The Relationship Between Metabolic Syndrome and Clinical Features of Non-alcoholic Fatty Liver Diseas

LI Ya-l

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Abstract

Objective: To investigate the relationship between metabolic syndrome and clinical features of non-alcoholic fatty liver disease. Methods: 326 patients with NAFLD diagnosed via ultrasound in physical examination data from January 2012 to February2012 were selected as the NAFLD group, and 335 patients without fatty liver were randomly selected as the control group.Clinical features between two groups of patients were observed, and the correlation between MS and NAFLD clinical features was analyzed by the Logistic regression analysis. Results: In NAFLD group, body mass index(BMI), blood pressure, alanine aminotransferase(ALT), fasting blood glucose(FBG), blood uric acid(UA), high-density lipoprotein(HDL- C), triglyceride(TG), aspartate aminotransferase(AST) were significantly higher than those of the control group(P0.05), there was no significant differences in low density lipoprotein cholesterol(LDL- C), total cholesterol(TC) between the two groups(P0.05). In NAFLD group, the detection rates of MS, abnormal blood lipid,abnormal glucose metabolism, obesity and hypertension were much higher than those of the control group(P0.05). The Logistic regression analysis showed that NAFLD, BMI, TG, HDL- C, high blood pressure and blood sugar were independent risk factors of MS. Conclusion: There are various and gathered characteristics components in patients with NAFLD, and the prevalence of MS increased significantly. NAFLD is one of the independent risk factors of MS, so MS is closely associated with NAFLD.

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What this paper is about

Objective: To investigate the relationship between metabolic syndrome and clinical features of non-alcoholic fatty liver disease. Methods: 326 patients with NAFLD diagnosed via ultrasound in physical examination data from January 2012 to February2012 were selected as the NAFLD group, and 335 patients without fatty liver were randomly selected as the control group.Clinical features between two groups of patients were observed, and the correlation between MS and NAFLD clinical features was analyzed by the Logistic regression analysis. Results: In NAFLD group, body mass index(BMI), blood pressure, alanine aminotransferase(ALT), fasting blood glucose(FBG), blood uric acid(UA), high-density lipoprotein(HDL- C), triglyceride(TG), aspartate aminotransferase(AST) were significantly higher than those of the control group(P0.05), there was no significant differences in low density lipoprotein cholesterol(LDL- C), total cholesterol(TC) between the two groups(P0.05). In NAFLD group, the detection rates of MS, abnormal blood lipid,abnormal glucose metabolism, obesity and hypertension were much higher than those of the control group(P0.05). The Logistic regression analysis showed that NAFLD, BMI, TG, HDL- C, high blood pressure and blood sugar were independent risk factors of MS. Conclusion: There are various and gathered characteristics components in patients with NAFLD, and the prevalence of MS increased significantly. NAFLD is one of the independent risk factors of MS, so MS is closely associated with NAFLD.

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Available abstract

Objective: To investigate the relationship between metabolic syndrome and clinical features of non-alcoholic fatty liver disease. Methods: 326 patients with NAFLD diagnosed via ultrasound in physical examination data from January 2012 to February2012 were selected as the NAFLD group, and 335 patients without fatty liver were randomly selected as the control group.Clinical features between two groups of patients were observed, and the correlation between MS and NAFLD clinical features was analyzed by the Logistic regression analysis. Results: In NAFLD group, body mass index(BMI), blood pressure, alanine aminotransferase(ALT), fasting blood glucose(FBG), blood uric acid(UA), high-density lipoprotein(HDL- C), triglyceride(TG), aspartate aminotransferase(AST) were significantly higher than those of the control group(P0.05), there was no significant differences in low density lipoprotein cholesterol(LDL- C), total cholesterol(TC) between the two groups(P0.05). In NAFLD group, the detection rates of MS, abnormal blood lipid,abnormal glucose metabolism, obesity and hypertension were much higher than those of the control group(P0.05). The Logistic regression analysis showed that NAFLD, BMI, TG, HDL- C, high blood pressure and blood sugar were independent risk factors of MS. Conclusion: There are various and gathered characteristics components in patients with NAFLD, and the prevalence of MS increased significantly. NAFLD is one of the independent risk factors of MS, so MS is closely associated with NAFLD.

Key concepts: Internal medicine, Fatty liver, Medicine, Triglyceride, Body mass index, Metabolic syndrome, Gastroenterology, Blood pressure

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