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A retrospective descriptive study on the significance of carbohydrate antigen 125 in differential diagnosis of high and low grade serous ovarian cancer

Xiaoya Liu

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Abstract

Objective To investigate the differential diagnosis significance of high and low grade serous ovarian cancer with carbohydrate antigen 125(CA125).Methods A total of 128 patients with ovarian tumors were retrospectively analyzed.The serum levels of CA125 of patients with high and low grade serous ovarian cancer and cystadenocarcinoma were determined preoperatively.Results Serum levels of CA125 among the high and low grade serous ovarian cancer patients were significantly higher than those of serous cystadenocarcinoma patients,respectively(P=0.002,P=0.003).The serum levels of CA125 between the high and low grade serous ovarian cancer patients showed no statistical significance(P=0.426).Conclusions Serum CA125 plays an important role in the differential diagnosis of malignant ovarian tumors,but it cannot identify the high and low grade serous ovarian cancer.

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What this paper is about

Objective To investigate the differential diagnosis significance of high and low grade serous ovarian cancer with carbohydrate antigen 125(CA125).Methods A total of 128 patients with ovarian tumors were retrospectively analyzed.The serum levels of CA125 of patients with high and low grade serous ovarian cancer and cystadenocarcinoma were determined preoperatively.Results Serum levels of CA125 among the high and low grade serous ovarian cancer patients were significantly higher than those of serous cystadenocarcinoma patients,respectively(P=0.002,P=0.003).The serum levels of CA125 between the high and low grade serous ovarian cancer patients showed no statistical significance(P=0.426).Conclusions Serum CA125 plays an important role in the differential diagnosis of malignant ovarian tumors,but it cannot identify the high and low grade serous ovarian cancer.

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Available abstract

Objective To investigate the differential diagnosis significance of high and low grade serous ovarian cancer with carbohydrate antigen 125(CA125).Methods A total of 128 patients with ovarian tumors were retrospectively analyzed.The serum levels of CA125 of patients with high and low grade serous ovarian cancer and cystadenocarcinoma were determined preoperatively.Results Serum levels of CA125 among the high and low grade serous ovarian cancer patients were significantly higher than those of serous cystadenocarcinoma patients,respectively(P=0.002,P=0.003).The serum levels of CA125 between the high and low grade serous ovarian cancer patients showed no statistical significance(P=0.426).Conclusions Serum CA125 plays an important role in the differential diagnosis of malignant ovarian tumors,but it cannot identify the high and low grade serous ovarian cancer.

Key concepts: Serous cystadenocarcinoma, Serous fluid, Cystadenocarcinoma, Medicine, Serous ovarian cancer, Ovarian cancer, Differential diagnosis, Cancer antigen

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A retrospective descriptive study on the significance of carbohydrate antigen 125 in differential diagnosis of high and low grade serous ovarian cancer — Research Paper | ScholarLens