Analysis on effectiveness of measles attenuated live vaccine supplementary immunization activities in Nanchang at 2009

Objective To evaluate the effectiveness of measles attenuated live vaccine(MV)supplementary immunization activities(SIA)in Nanchang in 2009 and provide basis for elimination measles.Method Collecting the data of basic investigation,scene vaccination and evaluation reports during measles vaccine supplementary immunization time of October 2009,all them comprehensive analysis with the data before and after supplementary immunization which collected from China Disease Prevention and Control Information System.Results This supplementary immunization had inoculation goal children 988 959 times,the reporting inoculation rate was 97.91%(988 959/1 010 096),the rapid assessment survey inoculation rate was 96.94%(1 745/1 800).MV SIA measles antibody positive rate,protection rate were 91.99%,70.51%,respectively.GMT antibody was raised from 1∶ 555 preimmune up to 1∶ 1625.28 after immunization,there was significant difference between the two(t=4.795,P=0.000).Total of 25 cases of adverse events following immunization(AEFI) were reported,the incidence rate was 2.53/10 million.10 measles cases were reported during November of 2009 to October of 2010 after supplementary immunization,the incidence rate was 0.20/10 million,the cases were lower than the same period of 2008 to 2009.Conclusions Quality MV SIA can rapidly improve the measles antibody level,lower incidence rate.Carrying out MV SIA was one of the safe and effective measures to accelerate measles control.