Analysis on the Correlation between Serum Uric Acid Level and Coronary Artery Disease

Objective:To evaluate the relationship between the serum uric acid(SUA) level and the severity of angiographic coronary artery disease(CAD).Method:We divided 266 patients who underwent coronary angiography into control group(n=79)and coronary atherosclerotic heart disease(CHD) group(n=187) in which patients were,in turn,divided into single-,double-and triple-vessel disease groups according to the number of vessels with significant stenosis.The serum uric acid level was determined,and the serum uric acid levels of different groups and the association between the serum uric acid level and coronary lesions were compared,and investigated the association between serum UA and the presence of CHD.Result:Serum UA level in CHD group,(399.06±96.32),μmoL/L was significantly higher than that in control group(308.45±72.85) μmoL/L,respectively and the serum uric acid levels between the two groups were significantly different(P0.01).The serum uric acid levels of the single-vessel group,double-vessel group and triple-vessel group were(386.23±87.04)μmoL/L,(397.76±95.30)μmoL/L,(416.06±80.72)μmoL/L,There was a trend of increase of UA level in the three groups,but respectively and the serum uric acid levels in the three groups were no significantly different(P0.05).Conclusion:The level of the UA is positively associated with the severity coronary artery lesion.