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2008•Journal of Kashgar Teachers CollegeRequires access

Mechanical Study on Translocation of DNA Through a Solid Nanopore

Hong Zhu

Open publisher page 1 citations

Abstract

Driving DNA through a synthetic solid nanopore is potentially a low-cost sequencing method.To achieve a single base-pair resolution,DNA's translocation velocity has to be controlled.I use a theoretical model to investigate the process of DNA translocation in a nanopore.Based on derived results,several methods to control the DNA translocation speed are suggested.

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What this paper is about

Driving DNA through a synthetic solid nanopore is potentially a low-cost sequencing method.To achieve a single base-pair resolution,DNA's translocation velocity has to be controlled.I use a theoretical model to investigate the process of DNA translocation in a nanopore.Based on derived results,several methods to control the DNA translocation speed are suggested.

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Available abstract

Driving DNA through a synthetic solid nanopore is potentially a low-cost sequencing method.To achieve a single base-pair resolution,DNA's translocation velocity has to be controlled.I use a theoretical model to investigate the process of DNA translocation in a nanopore.Based on derived results,several methods to control the DNA translocation speed are suggested.

Key concepts: Nanopore, Nanopore sequencing, Chromosomal translocation, DNA, DNA sequencing, Nanotechnology, Materials science, Biophysics

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