The variations of umbilical artery lactate level in newborn with intrapartum asphyxia and hypamnion

Objective To determine whether umbilical artery lactate level were significantly different in infant with or without intrapar-tum asphyxia and hypamnion.Method For 114 term parturients with cephalia precentation,singleton fetus,without obstetric and medical complications,newborn infant Apgar score≤7 were retrospectively analyzed,in which there were 57 cases in hypamnion group and 57 cases in normal amniotic fluid group.The lactate level and acid-base balance were measured at each delivery.At 4～6th and 26～28th days after birth,neonatal behavioral neudogioal assessment(NBNA) was taken for each newborn.Results There were significant differences in mean lactate level,pH value and BE in newborns with hypamnion compared with normal amniotic fluid group(P0.05).The lactate levels in hypamnion group was negatively correlated with the pH value and BE(r=-0.64 and-0.63,respectively,P0.05).There was no difference of NBNA score at the 4～6th and 26～28th days after birth with light-degree asphyxia between hypamnion group and normal amniotic fluid group(P0.05).But there were significant differences in serious asphyxia between the two groups(P0.05).Conclusion This study demonstrates that there are good correlation in umbilical artery lactate levels,pH value and BE in newborns,and there is obvious relation between hypamnion and lactic acid,which is the index of acute asphyxia.There is closely relation between NBNA score and asphyxia degree.