Analysis on infection distribution and the drug resistance of Pseudomonas aeruginosa

Objective To investigate the distribution and resistance of Pseudomonas aeruginosa, and to provide guidance for clinical treatment. Methods Pseudomonas aeruginosa was identified and its antimicrobial sensitivity test was determined by VITEK system. The antimicrobial ressistance rates were analyzed by WHONET software. Results Pseudomonas aeruginosa was the most detected in phlegm specimen (69.1%), followed by purulence (14.6%). Pseudomonas aeruginosa showed low resistance to Piperacillin/tazobactam (24.4%), imipenem (27.6%), amikacin (39.0%), ceftazidime (40.7%) and aztreonam (46.7%), and high resistance to ceftriaxone, cefepime, piperacillin, ticarcillin/clavulanic acid, gentamicin, tobramycin, ciprofloxacin and levofloxacin, with a resistance rate of 52.8%~92.7%. Conclusion The resistance of Pseudomonas aeruginosa is high. It is of great importance to use drugs rationally and enhance the monitoring of drug resistance.