Preparation and quality control of glucosamine hydrochloride dispersible tablets

Objective To analyze the preparation technology of glucosamine hydrochloride dispersible tablets and its quality control method.Methods Microcrystalline cellulose was selected as the diluent;sodium carboxymethyl starch,low-substituted hydroxypropylcellulose and crospovidone were selected as disintegrants;asipatan was selected as flavoring,peppermint oil was selected as aromatic,magnesium stearate was selected as lubricant,aerosil was selected as glidant.The contents of glucosamine hydrochloride dispersible tablets were determined by UV spectrophotomery.Results The glucosamine hydrochloride dispersible tablets can be obtained with good taste,smooth-surface and convenient in use.The linear range of glucosamine hydrochloride was 12～32mg/L(r=O.9998),the average rate of recovery was 99.65%,RSD was 0.35%(n=9).Conclusion The preparation technology is reliable,the methods are simple and accurate which can be used in hospital production and using.